姓名:卿志和
职称:教授
导师资格:博士生导师
邮箱:qingzhihe@hnu.edu.cn
电话:0731-85258649
研究方向:生物传感与健康分析
简介:卿志和,教授,博士生导师,国家优秀青年科学基金获得者,“细胞化学”湖南省重点实验室常务副主任,“健康化学”湖南省普通高等学校科技创新团队带头人,“食品安全”二级博士点方向带头人,长沙理工大学“湖湘学者”拔尖人才、化学化工学院副院长、院教授委员会主任、化学生物学专业负责人,全球前2%顶尖科学家。从事生物传感与健康分析研究工作,已主持国家自然科学基金优青项目、面上项目,湖南省自然科学基金重点项目、优青项目、企业技术服务项目等课题10余项,在 PNAS、Angew Chem、Nano Today、Chem Sci、Anal Chem、CCS Chem等国内外高水平期刊上发表SCI收录论文80余篇,授权专利10余件。获得湖南省自然科学一等奖、湖南省自然科学二等奖、湖南省青年科技奖、湖南省优秀博士学位论文奖、湖南省优秀硕士学位论文指导教师、湖南省优秀研究生导师、湖南省“挑战杯”创新创业大赛优秀指导教师、长沙市自然科学优秀学术成果一等奖、长沙理工大学优秀教师等奖励或荣誉。担任Chinese Chemical Letters、The Innovation、Journal of Analysis and Testing、《分析试验室》等国内外期刊的编委或青年编委。深入企业,努力推进产学研合作和成果转化,在生化传感、生物医药等相关领域产生经济效益和社会意义。
代表性论文:
[1] Yibo Zhou, Zhengxuan Gu, Changhui Liu, Sheng Yang,* Xiaofei Ma, Qiaoshu Chen, Yanli Lei, Ke Quan, Juewen Liu, Zhihe Qing,* Ronghua Yang*. A Polymeric Nanobeacon for Revealing Hydrogen Polysulfides Fluctuation during Fertilization and Embryonic Development. Angew. Chem. Int. Ed. 2022, DOI: 10.1002/anie.202114504.
[2] Zhen Zou, Libei He, Xiangxi Deng, Huangxiang Wang, Ziyun Huang, Qian Xue, Zhihe Qing*, Yanli Lei, Ronghua Yang*, and Juewen Liu. Zn2+-Coordination-Driven RNAAssembly with Retained Integrity and Biological Functions.Angew. Chem. Int. Ed.2021, 60, 22970–22976.
[3] Lifang Chen, Shuohui Xing, Yanli Lei, Qiaoshu Chen, Zhen Zou, Ke Quan, Zhihe Qing*, Juewen Liu, and Ronghua Yang*. A Glucose-Powered Activatable Nanozyme Breaking pH and H2O2 Limitations for Treating Diabetic Infections.Angew. Chem. Int. Ed.2021, 60, 23534–23539.
[4] Zhihe Qing, Guoyan Luo, Shuohui Xing, Zhen Zou, Yanli Lei, Juewen Liu*, Ronghua Yang*. Pt-S Bond Mediated Nanoflares for High-Fidelity Intracellular Applications by Avoiding Thiol Cleavage.Angew. Chem. Int. Ed.2020, 59, 14044 –14048.
[5] Zhihe Qing*, Jinlei Hu, Jingyuan Xu, Zhen Zou, Yanli Lei, Taiping Qing, Ronghua Yang*. An intramolecular catalytic hairpin assembly on a DNA tetrahedron for mRNA imaging in living cells: improving reaction kinetics and signal stability.Chem. Sci.2020, 11, 1985–1990.
[6] Zhihe Qing*, Jingyuan Xu, Jing Zheng, Lei He, Zhen Zou, Sheng Yang, Weihong Tan, Ronghua Yang*. In Situ Amplification-Based Imaging of RNA in Living Cells.Angew. Chem. Int. Ed.2019, 58, 11574–11585.