科研情况： ◉主要研究方向： 1、生物医药与化学生物传感 2、POCT(即时检测)产品的设计与实际应用 3、纳米药物载体的构建与应用 ◉近5年科研项目： 1、国家自然科学基金青年项目，核酸适体介导的邻近共价标记体系用于细胞生理活动的精准监测，执行时间：2024.01-2026.12；主持。 ◉近5年科研论文： 1.Kun Chen; Jiamin Cai; Sujuan Wang; et al. Aptamer inhibits tumor growth by leveraging cellular proteasomal degradation system to degrade c‐Met in mice, Angewandte Chemie International Edition, 2022, 62(2): e202208451. 2. Kun Chen; Qin Huang; Ting Fu; et al. MicroRNA-initiated and intracellular Na+-fueled DNAzyme motor for differentiating molecular subtypes of nonsmall cell lung cancer, Analytical Chemistry, 2020, 92(11): 7404-7408. 3. Kun Chen; Ting Fu; Weidi Sun; et al. DNA-supramolecule conjugates in theranostics, Theranostics, 2019, 9(11): 3262-3279 4. Kun Chen; Shuai Xu; Zhiling Song; et al. Trimethyl Lock Quinone-Based Organic Molecular Probes for NQO1 Sensing and Imaging. Chemosensors, 2023, 11(4): 221. 5. Chan Yang; Kun Chen; Mei Chen; et al. Nanoscale metal-organic framework based two-photon sensing platform for bioimaging in live tissue, Analytical Chemistry, 2019, 91(4): 2727-2733. |
